Tretinoin is a derivative of Vitamin A in the form of a topical prescription cream. Tretinoin is used in the treatment of mild to moderate acne, mild wrinkles and hyperpigmentation (brown spots)..

Tretinoin is also available under the following brand names Retin-A, Atralin, Renova, Avita and Altinac.

Tretinoin works by exfoliating the skin's outer layer and increases the turnover of skin cells. This helps to loosen the matter in blocked pores, and reduce the formation of blackheads, whiteheads and other acne lesions. It also increases blood vessel development and cell nutrition, decreases clogged pores and makes cells divide faster. It affects the depletion and dispersion of melanin and thickens and strengthens the skin tissues. Tretinoin can treat sun damaged skin by reducing wrinkles, lighten brown spots and smooth roughened areas of skin.

Side effects are usually mild, and may include darkening or lightening of the skin, burning, dryness, itching, peeling, redness, and stinging. These symptoms are common with patients with sensitive skin. The symptoms can be controlled by adjusting the frequency of application.

Tretinoin is usually applied once daily, in the evening. Patient should wash affected area of skin with mild soap and water before application. Wait approximately 30 minutes after washing, then gently rub a small amount of the cream or gel into the skin. Wash hands carefully immediately after.

It is very important that you inform your doctor of any medications you are currently taking before using Tretinoin. Pregnant or breastfeeding mothers are advised not to use Tretinoin, as there have been no studies done on the effects of Tretinoin on pregnant or nursing women.. Tretinoin should also not be used if the patient is taking other drugs that increase sensitivity to sunlight, including certain antibiotics suchas Cipro, Noroxin, and tetracycline, tranquilizers such as Thorazine and Mellaril, sulfa drugs such as Bactrim and Septra, and Thiazide drugs (water pills) such as Diuril and HydroDIURIL Other skin care regimes should not be combine with Tretinoin treatment, as Tretinoin can also interfere or have adverse interactions with certain ingredients used in other topical solutions, such as benzoyl peroxide, sulfur, Resorcinol, and Salicylic acid.

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